Tsukushi Makino is a tough, hard-working, lower-middle-class student at the prestigious escalator school Eitoku Gakuen. Initially, Makino wanted to attend Eitoku because her idol, an internationally renowned model named Shizuka Todou, was an alumna of the school. Not long after however, Makino discovers the superficial nature of her classmates. Their arrogance and her inability to relate to them because of her social status limit her chances to make friends. Worse yet, the school is ruled by the F4 or Flower Four, composed of playboys Soujiro Nishikado and Akira Mimasaka, introverted but intelligent and handsome Hanazawa Rui and violent and bratty Domyouji Tsukasa. The F4, sons of Japan's wealthiest and most powerful tycoons, bully fellow students out of boredom or malevolence until they are expelled or quit.

Makino's only wish is to remain invisible in Eitoku to avoid getting into trouble. However, she is immersed into the lives of the four legendary bullies after her first and only friend at school, Sakurako Sanjo, accidentally spills juice on Domyouji's white shirt in the cafeteria and she defends her. The next day, she receives a red tag in her locker (an order from the F4 to bully the target student by whatever means possible) and as a result, the whole school turns against her. Despite the harassment, Tsukushi, the "tough weed", refuses to give in or quit. After Domyouji treads all over the lobster her parents painstakingly cooked for her, she finally snaps, knocks him out and declares war on him. This unexpected retaliation catches him by surprise and causes him to fall in love with her. But Tsukushi has fallen in love with Rui, who in turn harbors romantic feelings for his childhood friend Shizuka.

The courtship between Tsukasa and Tsukushi is the main theme throughout the series. Various challenges threaten their blossoming relationship, including Tsukushi's wavering feelings for Rui, the envy of fellow Eitoku students, an obsessed childhood classmate, their differences in social class, Tsukasa's brash and possessive nature, and the animosity of Kaede Domyouji, Tsukasa's mother. The first season ends with Domyouji giving the saturn necklace to Makino and her confession of love right before he leaves for New York.

• Title:花より男子 - Hana Yori Dango
• Also known as: Boys before Flowers , Hana Yori Dango , Flowers over Boys , Hana Yori Dango Season 1
• Episodes: 9
• Genre: Drama, Comedy, Romance
• Viewership ratings: 14.9%
• Broadcast network: TBS
• Broadcast period: Oct 21, 2005 - Dec 16, 2005
• Air time: Friday 22:00
• Theme song: Wish by Arashi

Main cast

• Mao Inoue as Tsukushi Makino
• Jun Matsumoto as Tsukasa Domyouji
• Shun Oguri as Rui Hanazawa
• Shota Matsuda as Soujiro Nishikado
• Tsuyoshi Abe as Akira Mimasaka

• Aki Nishihara as Yuki Matsuoka
• Mayumi Sada as Todo Shizuka
• Seto Saki as Yuriko Asai
• Fukada Aki as Erika Ayuhara
• Matsuoka Emiko as Minako Yamano
• David Ito as Nishida
• Megumi Sato as Sakurako Sanjo
• Nanako Matsushima as Tsubaki Domyoji
• Mariko Kaga as Kaede Domyoji
• Takako Katou as Sachiyo Sengoku (Okami-San)
• Susumu Kobayashi as Haruo Makino
• Mako Ishino as Chieko Makino
• Satoshi Tomiura as Susumu Makino

• Based on the Boys Over Flowers Comics by: Yoko Kamio
• Screenwriters: Mikio Satake, Yuki Fujimoto, Natsuko Takahashi, Shūko Arai
• Producer: Katsuaki Setoguchi
• Directors: Yasuharu Ishii, Daisuke Yamamuro, Osamu Katayama
• Music: Kosuke Yamashita